Pyramidal Neurons Are Generated from Oligodendroglial Progenitor Cells in Adult Piriform Cortex

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Pyramidal neurons are generated from oligodendroglial progenitor cells in adult piriform cortex.

Previous studies have shown that oligodendroglial progenitor cells (OPCs) can give rise to neurons in vitro and in perinatal cerebral cortex in vivo. We now report that OPCs in adult murine piriform cortex express low levels of doublecortin, a marker for migratory and immature neurons. Additionally, these OPCs express Sox2, a neural stem cell marker, and Pax6, a transcription factor characteris...

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ژورنال

عنوان ژورنال: Journal of Neuroscience

سال: 2010

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.1360-10.2010